Pipeline Overview

GLA-H Gene Therapy

Transplantation therapy using hematopoietic stem cells (HSCs) engineered to restore alpha-galactosidase A (a-gal A) enzyme activity in patients.


GLA-T Gene Therapy

Cell therapy using rapamycin-attenuated T cells engineered to restore a-gal A enzyme activity in patients.


GLA-S Substrate Reduction Therapy

Modulation of gene expression to alter metabolic pathways and reduced the substrate for a-gal A enzyme.